diff --git a/Include/Python.h b/Include/Python.h
index a83befa31173..d3186c32e355 100644
--- a/Include/Python.h
+++ b/Include/Python.h
@@ -106,6 +106,7 @@
 #include "sliceobject.h"
 #include "cellobject.h"
 #include "iterobject.h"
+#include "cpython/initconfig.h"
 #include "genobject.h"
 #include "descrobject.h"
 #include "genericaliasobject.h"
@@ -118,8 +119,6 @@
 
 #include "codecs.h"
 #include "pyerrors.h"
-
-#include "cpython/initconfig.h"
 #include "pythread.h"
 #include "pystate.h"
 #include "context.h"
diff --git a/Include/cpython/pystate.h b/Include/cpython/pystate.h
index b0d30bd07931..7c995b93074f 100644
--- a/Include/cpython/pystate.h
+++ b/Include/cpython/pystate.h
@@ -2,8 +2,6 @@
 #  error "this header file must not be included directly"
 #endif
 
-#include "cpython/initconfig.h"
-
 PyAPI_FUNC(int) _PyInterpreterState_RequiresIDRef(PyInterpreterState *);
 PyAPI_FUNC(void) _PyInterpreterState_RequireIDRef(PyInterpreterState *, int);
 
diff --git a/Misc/NEWS.d/next/C API/2021-11-09-15-42-11.bpo-39026.sUnYWn.rst b/Misc/NEWS.d/next/C API/2021-11-09-15-42-11.bpo-39026.sUnYWn.rst
new file mode 100644
index 000000000000..77a011979215
--- /dev/null
+++ b/Misc/NEWS.d/next/C API/2021-11-09-15-42-11.bpo-39026.sUnYWn.rst	
@@ -0,0 +1,2 @@
+Fix Python.h to build C extensions with Xcode: remove a relative include
+from ``Include/cpython/pystate.h``.