diff --git a/packages/runtime-core/src/renderer.ts b/packages/runtime-core/src/renderer.ts
index 4d224e405..48336ebb9 100644
--- a/packages/runtime-core/src/renderer.ts
+++ b/packages/runtime-core/src/renderer.ts
@@ -311,9 +311,7 @@ export const setRef = (
     if (isString(oldRef)) {
       refs[oldRef] = null
       if (hasOwn(setupState, oldRef)) {
-        queuePostRenderEffect(() => {
-          setupState[oldRef] = null
-        }, parentSuspense)
+        setupState[oldRef] = null
       }
     } else if (isRef(oldRef)) {
       oldRef.value = null