diff --git a/src/qemu/qemu_validate.c b/src/qemu/qemu_validate.c
index 488f258d00..cac60e3394 100644
--- a/src/qemu/qemu_validate.c
+++ b/src/qemu/qemu_validate.c
@@ -4012,15 +4012,45 @@ qemuValidateDomainDeviceDefHub(virDomainHubDefPtr hub,
 }
 
 
+static unsigned long long
+qemuValidateGetNVDIMMAlignedSizePseries(virDomainMemoryDefPtr mem,
+                                        const virDomainDef *def)
+{
+    unsigned long long ppc64AlignSize = qemuDomainGetMemorySizeAlignment(def);
+    unsigned long long guestArea = mem->size - mem->labelsize;
+
+    /* NVDIMM is already aligned */
+    if (guestArea % ppc64AlignSize == 0)
+        return mem->size;
+
+    /* Suggested aligned size is rounded up */
+    guestArea = (guestArea/ppc64AlignSize + 1) * ppc64AlignSize;
+    return guestArea + mem->labelsize;
+}
+
 static int
 qemuValidateDomainDeviceDefMemory(virDomainMemoryDefPtr mem,
+                                  const virDomainDef *def,
                                   virQEMUCapsPtr qemuCaps)
 {
-    if (mem->model == VIR_DOMAIN_MEMORY_MODEL_NVDIMM &&
-        !virQEMUCapsGet(qemuCaps, QEMU_CAPS_DEVICE_NVDIMM)) {
-        virReportError(VIR_ERR_CONFIG_UNSUPPORTED, "%s",
-                       _("nvdimm isn't supported by this QEMU binary"));
-        return -1;
+    if (mem->model == VIR_DOMAIN_MEMORY_MODEL_NVDIMM) {
+        if (!virQEMUCapsGet(qemuCaps, QEMU_CAPS_DEVICE_NVDIMM)) {
+            virReportError(VIR_ERR_CONFIG_UNSUPPORTED, "%s",
+                           _("nvdimm isn't supported by this QEMU binary"));
+            return -1;
+        }
+
+        if (qemuDomainIsPSeries(def)) {
+            unsigned long long alignedNVDIMMSize =
+                qemuValidateGetNVDIMMAlignedSizePseries(mem, def);
+
+            if (mem->size != alignedNVDIMMSize) {
+                virReportError(VIR_ERR_CONFIG_UNSUPPORTED,
+                               _("nvdimm size is not aligned. Suggested aligned "
+                                 "size: %llu KiB"), alignedNVDIMMSize);
+                return -1;
+            }
+        }
     }
 
     return 0;
@@ -4138,7 +4168,7 @@ qemuValidateDomainDeviceDef(const virDomainDeviceDef *dev,
         break;
 
     case VIR_DOMAIN_DEVICE_MEMORY:
-        ret = qemuValidateDomainDeviceDefMemory(dev->data.memory, qemuCaps);
+        ret = qemuValidateDomainDeviceDefMemory(dev->data.memory, def, qemuCaps);
         break;
 
     case VIR_DOMAIN_DEVICE_LEASE:
diff --git a/tests/qemuxml2argvdata/memory-hotplug-nvdimm-ppc64.ppc64-latest.args b/tests/qemuxml2argvdata/memory-hotplug-nvdimm-ppc64.ppc64-latest.args
index eff80dcf80..58e3f9e161 100644
--- a/tests/qemuxml2argvdata/memory-hotplug-nvdimm-ppc64.ppc64-latest.args
+++ b/tests/qemuxml2argvdata/memory-hotplug-nvdimm-ppc64.ppc64-latest.args
@@ -19,7 +19,7 @@ file=/tmp/lib/domain--1-QEMUGuest1/master-key.aes \
 -smp 2,sockets=2,dies=1,cores=1,threads=1 \
 -numa node,nodeid=0,cpus=0-1,mem=1024 \
 -object memory-backend-file,id=memnvdimm0,prealloc=yes,mem-path=/tmp/nvdimm,\
-size=537001984 \
+size=805437440 \
 -device nvdimm,node=0,label-size=131072,\
 uuid=49545eb3-75e1-2d0a-acdd-f0294406c99e,memdev=memnvdimm0,id=nvdimm0,slot=0 \
 -uuid c7a5fdbd-edaf-9455-926a-d65c16db1809 \
diff --git a/tests/qemuxml2argvdata/memory-hotplug-nvdimm-ppc64.xml b/tests/qemuxml2argvdata/memory-hotplug-nvdimm-ppc64.xml
index ae5a17d3c8..10c146e8cf 100644
--- a/tests/qemuxml2argvdata/memory-hotplug-nvdimm-ppc64.xml
+++ b/tests/qemuxml2argvdata/memory-hotplug-nvdimm-ppc64.xml
@@ -38,7 +38,7 @@
         <path>/tmp/nvdimm</path>
       </source>
       <target>
-        <size unit='KiB'>550000</size>
+        <size unit='KiB'>786560</size>
         <node>0</node>
         <label>
           <size unit='KiB'>128</size>
diff --git a/tests/qemuxml2xmloutdata/memory-hotplug-nvdimm-ppc64.xml b/tests/qemuxml2xmloutdata/memory-hotplug-nvdimm-ppc64.xml
index ae5a17d3c8..10c146e8cf 100644
--- a/tests/qemuxml2xmloutdata/memory-hotplug-nvdimm-ppc64.xml
+++ b/tests/qemuxml2xmloutdata/memory-hotplug-nvdimm-ppc64.xml
@@ -38,7 +38,7 @@
         <path>/tmp/nvdimm</path>
       </source>
       <target>
-        <size unit='KiB'>550000</size>
+        <size unit='KiB'>786560</size>
         <node>0</node>
         <label>
           <size unit='KiB'>128</size>