diff --git a/core/app_prebuilt_internal.mk b/core/app_prebuilt_internal.mk
index ad96b5b54..d47930c84 100644
--- a/core/app_prebuilt_internal.mk
+++ b/core/app_prebuilt_internal.mk
@@ -102,6 +102,15 @@ ifndef LOCAL_ENFORCE_USES_LIBRARIES
   endif
 endif
 
+# Disable verify_uses_libraries check if dexpreopt is globally disabled.
+# Without dexpreopt the check is not necessary, and although it is good to have,
+# it is difficult to maintain on non-linux build platforms where dexpreopt is
+# generally disabled (the check may fail due to various unrelated reasons, such
+# as a failure to get manifest from an APK).
+ifneq ($(WITH_DEXPREOPT),true)
+  LOCAL_ENFORCE_USES_LIBRARIES :=
+endif
+
 my_enforced_uses_libraries :=
 ifdef LOCAL_ENFORCE_USES_LIBRARIES
   my_enforced_uses_libraries := $(intermediates.COMMON)/enforce_uses_libraries.status