diff --git a/rust/bindgen.go b/rust/bindgen.go
index 2224a9cca..74b2777c3 100644
--- a/rust/bindgen.go
+++ b/rust/bindgen.go
@@ -18,6 +18,7 @@ import (
 	"strings"
 
 	"github.com/google/blueprint"
+	"github.com/google/blueprint/proptools"
 
 	"android/soong/android"
 	ccConfig "android/soong/cc/config"
@@ -119,15 +120,17 @@ func (b *bindgenDecorator) generateSource(ctx android.ModuleContext, deps PathDe
 		cflags = append(cflags, "-isystem "+include.String())
 	}
 
+	esc := proptools.NinjaAndShellEscapeList
+
 	// Module defined clang flags and include paths
-	cflags = append(cflags, b.Properties.Cflags...)
+	cflags = append(cflags, esc(b.Properties.Cflags)...)
 	for _, include := range b.Properties.Local_include_dirs {
 		cflags = append(cflags, "-I"+android.PathForModuleSrc(ctx, include).String())
 		implicits = append(implicits, android.PathForModuleSrc(ctx, include))
 	}
 
 	bindgenFlags := defaultBindgenFlags
-	bindgenFlags = append(bindgenFlags, strings.Join(b.Properties.Bindgen_flags, " "))
+	bindgenFlags = append(bindgenFlags, esc(b.Properties.Bindgen_flags)...)
 
 	wrapperFile := android.OptionalPathForModuleSrc(ctx, b.Properties.Wrapper_src)
 	if !wrapperFile.Valid() {
diff --git a/rust/bindgen_test.go b/rust/bindgen_test.go
index 0b529ca5a..191da9b11 100644
--- a/rust/bindgen_test.go
+++ b/rust/bindgen_test.go
@@ -27,8 +27,8 @@ func TestRustBindgen(t *testing.T) {
 			crate_name: "bindgen",
 			stem: "libbindgen",
 			source_stem: "bindings",
-			bindgen_flags: ["--bindgen-flag"],
-			cflags: ["--clang-flag"],
+			bindgen_flags: ["--bindgen-flag.*"],
+			cflags: ["--clang-flag()"],
 			shared_libs: ["libfoo_shared"],
 			static_libs: ["libfoo_static"],
 		}
@@ -42,10 +42,11 @@ func TestRustBindgen(t *testing.T) {
 		}
 	`)
 	libbindgen := ctx.ModuleForTests("libbindgen", "android_arm64_armv8-a").Output("bindings.rs")
-	if !strings.Contains(libbindgen.Args["flags"], "--bindgen-flag") {
+	// Ensure that the flags are present and escaped
+	if !strings.Contains(libbindgen.Args["flags"], "'--bindgen-flag.*'") {
 		t.Errorf("missing bindgen flags in rust_bindgen rule: flags %#v", libbindgen.Args["flags"])
 	}
-	if !strings.Contains(libbindgen.Args["cflags"], "--clang-flag") {
+	if !strings.Contains(libbindgen.Args["cflags"], "'--clang-flag()'") {
 		t.Errorf("missing clang cflags in rust_bindgen rule: cflags %#v", libbindgen.Args["cflags"])
 	}
 	if !strings.Contains(libbindgen.Args["cflags"], "-Ishared_include") {